Air Europa
SkyTeam
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Panama
Tocumen International Airport
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Spain
Madrid-Barajas Airport
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Scan through all non-stop flights from Panama City to Madrid. The full flight schedule below gives an overview of all non-stop flights from PTY to MAD, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
The Mediterranean regions near Madrid are known for their warm, arid summers, where temperatures often go beyond 30°C (86°F). In some inland spots, the heat can climb even higher, sometimes reaching 40°C (104°F) or more. The winters are pleasantly mild, accompanied by some rainfall. This lovely climate, paired with breathtaking landscapes and bright, sunny days attract visitors from around the globe.
Madrid is a wonderful place to visit all year long, but spring (March-May) and fall (September-November) are the best seasons to visit. The weather is pleasantly warm during these times, especially since the summers can be quite hot in those regions.
In total there are 2 airlines operating nonstop flights from Panama City PTY to Madrid MAD. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their PTY MAD flight schedule.
Flights from PTY to MAD are operated 10 times a week, with an average of 1 flight per day. Departure times vary between 20:25 - 22:35. The earliest flight departs at 20:25, the last flight departs at 22:35. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy, Premium Economy and Business Class. First Class is not available on this route (at least not as a non-stop flight).
The fastest direct flight from Panama City to Madrid takes 9 hours and 35 minutes. The flight distance between Panama City and Madrid is 5,066 miles (or 8,153 km).
There is 1 airport in Madrid: Madrid-Barajas Airport (MAD).
There are 10 flights per week flying from Panama City to Madrid (as of April 2026).
9 hours and 35 minutes is the average flight time from Panama City to Madrid.
The distance from Panama City to Madrid is 5,066 miles (8,153 kilometers).
Air Europa and Iberia are flying nonstop from Panama City to Madrid.
Oneworld and SkyTeam are flying nonstop from Panama City to Madrid.
You can fly non-stop in Economy, Premium Economy and Business Class.
Aircraft types that fly from Panama City to Madrid:
The earliest flight departs at 20:25 from Panama City and arrives at 13:15 at Madrid.
The latest flight departs at 22:35 from Panama City and arrives at 14:40 at Madrid.
5,066 miles (8,153 km) · 9h 35m
20:25
13:15
Air Europa
SkyTeam
UX 56
Air Europa
Boeing 787-8
Y
W
J
F
20:25
13:15
Air Europa
SkyTeam
UX 56
Air Europa
Boeing 787-9
Y
W
J
F
20:25
13:15
Air Europa
SkyTeam
UX 56
Air Europa
Boeing 787-8
Y
W
J
F
20:25
13:15
Air Europa
SkyTeam
UX 56
Air Europa
Boeing 787-9
Y
W
J
F
20:25
13:15
Air Europa
SkyTeam
UX 56
Air Europa
Boeing 787-9
Y
W
J
F
20:25
13:15
Air Europa
SkyTeam
UX 56
Air Europa
Boeing 787-8
Y
W
J
F
20:25
13:15
Air Europa
SkyTeam
UX 56
Air Europa
Boeing 787-8
Y
W
J
F
20:25
13:15
Air Europa
SkyTeam
UX 56
Air Europa
Boeing 787-9
Y
W
J
F
21:30
14:20
Iberia
Oneworld
IB 258
Iberia
Airbus A330
Y
W
J
F
21:30
14:20
Iberia
Oneworld
IB 258
Iberia
Airbus A330-200
Y
W
J
F
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