Southwest Airlines
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United States
Des Moines International Airport
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Scan through all non-stop flights from Chicago to Des Moines. The full flight schedule below gives an overview of all non-stop flights from MDW to DSM, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Known for its continental climate, Des Moines features hot, humid summers with temperatures above 30°C (86°F) and cold, snowy winters that often drop below 0°C (32°F). This striking seasonal contrast offers travelers a variety of activities, from summer hiking to winter sports, ensuring year-round appeal.
The best time to visit Des Moines is from March to November, covering spring, summer, and fall. While summer can be hot, it also sees slightly more rainfall than other seasons.
Currently, there is only one airline operating non-stop flights from Chicago MDW to Des Moines DSM, which is Southwest Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their MDW DSM flight schedule.
Flights from MDW to DSM are operated 13 times a week, with an average of 2 flights per day. Departure times vary between 09:50 - 22:25. The earliest flight departs at 09:50, the last flight departs at 22:25. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from Chicago to Des Moines takes 1 hour and 25 minutes. The flight distance between Chicago and Des Moines is 305 miles (or 491 km).
There is 1 airport in Des Moines: Des Moines International Airport (DSM).
There are 13 flights per week flying from Chicago to Des Moines (as of April 2026).
1 hour and 25 minutes is the average flight time from Chicago to Des Moines.
The distance from Chicago to Des Moines is 305 miles (491 kilometers).
Southwest Airlines is the only airline flying nonstop from Chicago to Des Moines.
There are no alliances flying direct from Chicago to Des Moines at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from Chicago to Des Moines:
The earliest flight departs at 09:50 from Chicago and arrives at 11:20 at Des Moines.
The latest flight departs at 22:25 from Chicago and arrives at 23:45 at Des Moines.
305 miles (491 km) · 1h 25m
10:00
11:25
Southwest Airlines
WN 1150
Southwest Airlines
Boeing 757
Y
W
J
F
10:00
11:25
Southwest Airlines
WN 869
Southwest Airlines
Boeing 757
Y
W
J
F
10:05
11:30
Southwest Airlines
WN 2387
Southwest Airlines
Boeing 757
Y
W
J
F
10:05
11:30
Southwest Airlines
WN 4248
Southwest Airlines
Boeing 757
Y
W
J
F
10:05
11:30
Southwest Airlines
WN 1150
Southwest Airlines
Boeing 757
Y
W
J
F
10:20
11:45
Southwest Airlines
WN 2127
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
10:45
12:10
Southwest Airlines
WN 2387
Southwest Airlines
Boeing 757
Y
W
J
F
20:50
22:10
Southwest Airlines
WN 2062
Southwest Airlines
Boeing 757
Y
W
J
F
21:25
22:50
Southwest Airlines
WN 1779
Southwest Airlines
Boeing 757
Y
W
J
F
21:45
23:05
Southwest Airlines
WN 2062
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
21:50
23:15
Southwest Airlines
WN 1779
Southwest Airlines
Boeing 757
Y
W
J
F
21:55
23:20
Southwest Airlines
WN 2062
Southwest Airlines
Boeing 737-800 (winglets)
Y
W
J
F
22:10
23:35
Southwest Airlines
WN 1779
Southwest Airlines
Boeing 757
Y
W
J
F
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