JetSmart
Did you mean flights from Medellín to Santiago de Chile?
Chile
Comodoro Arturo Merino Benítez International Airport
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Colombia
José María Córdova International Airport
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Scan through all non-stop flights from Santiago de Chile to Medellín. The full flight schedule below gives an overview of all non-stop flights from SCL to MDE, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Medellín is an oceanic/maritime destination, known for its mild summer temperatures, which are usually between 15°C and 25°C (59°F to 77°F). The winters here are refreshingly cool, without the harshness of freezing temperatures. Visitors can enjoy the green surroundings and plenty of outdoor adventures in the nearby areas, making it an excellent choice for those who enjoy temperate weather.
The best time to visit Medellín is during the summer months, spanning from May to August. During this period, visitors can expect pleasant to warm temperatures, while rainfall tends to occur more frequently in the autumn and winter months, from September to February.

Currently, there is only one airline operating non-stop flights from Santiago de Chile SCL to Medellín MDE, which is JetSmart. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their SCL MDE flight schedule.
Flights from SCL to MDE are operated 3 times a week, with an average of 1 flight per day. Departure times vary between 01:11 - 02:11. The earliest flight departs at 01:11, the last flight departs at 02:11. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from Santiago de Chile to Medellín takes 6 hours and 15 minutes. The flight distance between Santiago de Chile and Medellín is 2,748 miles (or 4,422 km).
There are 2 airports in Medellín: José María Córdova International Airport (MDE) and Olaya Herrera Airport (EOH).
There are 3 flights per week flying from Santiago de Chile to Medellín (as of March 2026).
6 hours and 15 minutes is the average flight time from Santiago de Chile to Medellín.
The distance from Santiago de Chile to Medellín is 2,748 miles (4,422 kilometers).
JetSmart is the only airline flying nonstop from Santiago de Chile to Medellín.
There are no alliances flying direct from Santiago de Chile to Medellín at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from Santiago de Chile to Medellín:
The earliest flight departs at 01:11 from Santiago de Chile and arrives at 06:35 at Medellín.
The latest flight departs at 02:11 from Santiago de Chile and arrives at 06:35 at Medellín.
2,748 miles (4,422 km) · 6h 15m
02:09
06:24
JetSmart
JA 5839
JetSmart
Airbus A320-100/200
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