LATAM
Did you mean flights from Antofagasta to La Serena?
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La Florida Airport
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Chile
Cerro Moreno International Airpor
Click to show full flight schedule
Scan through all non-stop flights from La Serena to Antofagasta. The full flight schedule below gives an overview of all non-stop flights from LSC to ANF, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Desert destinations like Antofagasta are known for their hot days, with temperatures frequently exceeding 40°C (104°F), but cooler nights. With very little rainfall, these locations are famous for their extreme weather, breathtaking scenery, and the cultural heritage of their inhabitants. Despite the harsh living conditions, they provide a remarkable mix of adventure, calmness, and stunning landscapes, making them wonderful places to explore.
Antofagasta is a wonderful destination to explore throughout the year, but it's advisable to avoid the summer months due to the intense heat. For a more enjoyable visit, plan your trip between March and November.

In total there are 3 airlines operating nonstop flights from La Serena LSC to Antofagasta ANF. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their LSC ANF flight schedule.
Flights from LSC to ANF are operated 19 times a week, with an average of 3 flights per day. Departure times vary between 09:38 - 21:21. The earliest flight departs at 09:38, the last flight departs at 21:21. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from La Serena to Antofagasta takes 1 hour and 18 minutes. The flight distance between La Serena and Antofagasta is 449 miles (or 723 km).
There is 1 airport in Antofagasta: Cerro Moreno International Airpor (ANF).
There are 19 flights per week flying from La Serena to Antofagasta (as of April 2026).
1 hour and 18 minutes is the average flight time from La Serena to Antofagasta.
The distance from La Serena to Antofagasta is 449 miles (723 kilometers).
JetSmart, LATAM and Sky Airline are flying nonstop from La Serena to Antofagasta.
There are no alliances flying direct from La Serena to Antofagasta at the moment.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from La Serena to Antofagasta:
The earliest flight departs at 09:38 from La Serena and arrives at 10:56 at Antofagasta.
The latest flight departs at 21:21 from La Serena and arrives at 22:43 at Antofagasta.
449 miles (723 km) · 1h 18m
10:37
11:55
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10:37
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10:38
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JA 140
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10:38
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10:42
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10:44
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11:11
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11:21
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11:34
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17:57
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18:16
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20:02
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