Copa Airlines
Star Alliance
Did you mean flights from Cali to Panama City?
Panama
Tocumen International Airport
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Colombia
Alfonso Bonilla Aragón International Airport
Click to show full flight schedule
Scan through all non-stop flights from Panama City to Cali. The full flight schedule below gives an overview of all non-stop flights from PTY to CLO, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Cali is a tropical destination known for its warm climate, with temperatures between 25°C and 30°C (77°F to 86°F) throughout the year. The area is characterized by high humidity and frequent rainfall.
Being located north of the equator, Cali experiences its dry season from November to April, making this the perfect time to visit. In this period, you can expect mostly dry conditions, while the wet season will see days of rain. Humidity and temperatures are consistently high all year long.

Currently, there is only one airline operating non-stop flights from Panama City PTY to Cali CLO, which is Copa Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their PTY CLO flight schedule.
Flights from PTY to CLO are operated 28 times a week, with an average of 4 flights per day. Departure times vary between 09:20 - 21:55. The earliest flight departs at 09:20, the last flight departs at 21:55. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Panama City to Cali takes 1 hour and 41 minutes. The flight distance between Panama City and Cali is 433 miles (or 697 km).
There is 1 airport in Cali: Alfonso Bonilla Aragón International Airport (CLO).
There are 28 flights per week flying from Panama City to Cali (as of April 2026).
1 hour and 41 minutes is the average flight time from Panama City to Cali.
The distance from Panama City to Cali is 433 miles (697 kilometers).
Copa Airlines is the only airline flying nonstop from Panama City to Cali.
Star Alliance is currently the only alliance flying nonstop from Panama City to Cali.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Panama City to Cali:
The earliest flight departs at 09:20 from Panama City and arrives at 11:00 at Cali.
The latest flight departs at 21:55 from Panama City and arrives at 23:36 at Cali.
433 miles (697 km) · 1h 41m
09:25
11:06
Copa Airlines
Star Alliance
CM 282
Copa Airlines
Boeing 737-700
Y
W
J
F
09:25
11:06
Copa Airlines
Star Alliance
CM 282
Copa Airlines
Boeing 737 MAX 9
Y
W
J
F
09:25
11:06
Copa Airlines
Star Alliance
CM 282
Copa Airlines
Boeing 737 MAX 9
Y
W
J
F
09:25
11:06
Copa Airlines
Star Alliance
CM 282
Copa Airlines
Boeing 737-800
Y
W
J
F
09:25
11:06
Copa Airlines
Star Alliance
CM 282
Copa Airlines
Boeing 737 MAX 9
Y
W
J
F
09:25
11:06
Copa Airlines
Star Alliance
CM 282
Copa Airlines
Boeing 737 MAX 9
Y
W
J
F
09:25
11:06
Copa Airlines
Star Alliance
CM 282
Copa Airlines
Boeing 737-800
Y
W
J
F
09:25
11:06
Copa Airlines
Star Alliance
CM 282
Copa Airlines
Boeing 737 MAX 9
Y
W
J
F
09:25
11:06
Copa Airlines
Star Alliance
CM 282
Copa Airlines
Boeing 737-800
Y
W
J
F
12:29
14:10
Copa Airlines
Star Alliance
CM 307
Copa Airlines
Boeing 737-800
Y
W
J
F
12:29
14:10
Copa Airlines
Star Alliance
CM 307
Copa Airlines
Boeing 737-800
Y
W
J
F
12:29
14:10
Copa Airlines
Star Alliance
CM 307
Copa Airlines
Boeing 737-800
Y
W
J
F
12:29
14:10
Copa Airlines
Star Alliance
CM 307
Copa Airlines
Boeing 737-700
Y
W
J
F
12:29
14:10
Copa Airlines
Star Alliance
CM 307
Copa Airlines
Boeing 737-800
Y
W
J
F
12:29
14:10
Copa Airlines
Star Alliance
CM 307
Copa Airlines
Boeing 737-800
Y
W
J
F
15:55
17:36
Copa Airlines
Star Alliance
CM 830
Copa Airlines
Boeing 737-800
Y
W
J
F
15:55
17:36
Copa Airlines
Star Alliance
CM 830
Copa Airlines
Boeing 737-800
Y
W
J
F
15:55
17:36
Copa Airlines
Star Alliance
CM 363
Copa Airlines
Boeing 737-700
Y
W
J
F
15:55
17:36
Copa Airlines
Star Alliance
CM 830
Copa Airlines
Boeing 737-800
Y
W
J
F
15:55
17:36
Copa Airlines
Star Alliance
CM 830
Copa Airlines
Boeing 737-800
Y
W
J
F
15:55
17:36
Copa Airlines
Star Alliance
CM 830
Copa Airlines
Boeing 737-800
Y
W
J
F
15:55
17:36
Copa Airlines
Star Alliance
CM 830
Copa Airlines
Boeing 737-800
Y
W
J
F
21:55
23:36
Copa Airlines
Star Alliance
CM 323
Copa Airlines
Boeing 737-800
Y
W
J
F
21:55
23:36
Copa Airlines
Star Alliance
CM 323
Copa Airlines
Boeing 737-800
Y
W
J
F
21:55
23:36
Copa Airlines
Star Alliance
CM 323
Copa Airlines
Boeing 737-800
Y
W
J
F
21:55
23:36
Copa Airlines
Star Alliance
CM 323
Copa Airlines
Boeing 737-800
Y
W
J
F
21:55
23:36
Copa Airlines
Star Alliance
CM 323
Copa Airlines
Boeing 737-800
Y
W
J
F
21:55
23:36
Copa Airlines
Star Alliance
CM 323
Copa Airlines
Boeing 737-800
Y
W
J
F
21:55
23:36
Copa Airlines
Star Alliance
CM 323
Copa Airlines
Boeing 737-800
Y
W
J
F
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