Allegiant
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United States
McGhee Tyson Airport
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United States
William P. Hobby Airport
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Scan through all non-stop flights from Knoxville to Houston. The full flight schedule below gives an overview of all non-stop flights from TYS to HOU, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Houston is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit Houston any time of the year, but the best months to explore are from to and from to .
Currently, there is only one airline operating non-stop flights from Knoxville TYS to Houston HOU, which is Allegiant. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their TYS HOU flight schedule.
Flights from TYS to HOU are operated once a week. Departure times vary between 10:00 - 18:28. The earliest flight departs at 10:00, the last flight departs at 18:28. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from Knoxville to Houston takes 2 hours and 20 minutes. The flight distance between Knoxville and Houston is 780 miles (or 1,255 km).
There are 2 airports in Houston: William P. Hobby Airport (HOU) and George Bush Intercontinental Airport (IAH).
There is 1 flight per week flying from Knoxville to Houston (as of April 2026).
2 hours and 20 minutes is the average flight time from Knoxville to Houston.
The distance from Knoxville to Houston is 780 miles (1,255 kilometers).
Allegiant is the only airline flying nonstop from Knoxville to Houston.
There are no alliances flying direct from Knoxville to Houston at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from Knoxville to Houston:
The earliest flight departs at 10:00 from Knoxville and arrives at 11:20 at Houston.
The latest flight departs at 18:28 from Knoxville and arrives at 19:45 at Houston.
780 miles (1,255 km) · 2h 20m
17:30
18:49
Allegiant
G4 1428
Allegiant
Airbus A320-100/200
Y
W
J
F
17:30
18:49
Allegiant
G4 3059
Allegiant
Airbus A320-100/200
Y
W
J
F
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