Delta
SkyTeam
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United States
McGhee Tyson Airport
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United States
Minneapolis-Saint Paul International Airport
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Scan through all non-stop flights from Knoxville to Minneapolis. The full flight schedule below gives an overview of all non-stop flights from TYS to MSP, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Known for its continental climate, Minneapolis features hot, humid summers with temperatures above 30°C (86°F) and cold, snowy winters that often drop below 0°C (32°F). This striking seasonal contrast offers travelers a variety of activities, from summer hiking to winter sports, ensuring year-round appeal.
The best time to visit Minneapolis is from March to November, covering spring, summer, and fall. While summer can be hot, it also sees slightly more rainfall than other seasons.
Currently, there is only one airline operating non-stop flights from Knoxville TYS to Minneapolis MSP, which is Delta. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their TYS MSP flight schedule.
Flights from TYS to MSP are operated 7 times a week, with an average of 1 flight per day. Departure times vary between 06:15 - 18:15. The earliest flight departs at 06:15, the last flight departs at 18:15. However, this depends on the date you are flying so please check with the full flight schedule above to see which departure times are available on your preferred date(s) of travel.
You can fly in Economy and Business Class. Premium Economy and First Class are not available on this route (at least not as a non-stop flight).
The fastest direct flight from Knoxville to Minneapolis takes 2 hours and 32 minutes. The flight distance between Knoxville and Minneapolis is 791 miles (or 1,273 km).
There is 1 airport in Minneapolis: Minneapolis-Saint Paul International Airport (MSP).
There are 7 flights per week flying from Knoxville to Minneapolis (as of April 2026).
2 hours and 32 minutes is the average flight time from Knoxville to Minneapolis.
The distance from Knoxville to Minneapolis is 791 miles (1,273 kilometers).
Delta is the only airline flying nonstop from Knoxville to Minneapolis.
SkyTeam is currently the only alliance flying nonstop from Knoxville to Minneapolis.
You can fly non-stop in Economy and Business Class.
Aircraft types that fly from Knoxville to Minneapolis:
The earliest flight departs at 06:15 from Knoxville and arrives at 07:44 at Minneapolis.
The latest flight departs at 18:15 from Knoxville and arrives at 19:47 at Minneapolis.
791 miles (1,273 km) · 2h 32m
06:15
07:44
Delta
SkyTeam
DL 5523
Delta
Canadair Regional Jet 900
Y
W
J
F
06:20
07:44
Delta
SkyTeam
DL 5523
Delta
Canadair Regional Jet 900
Y
W
J
F
06:35
08:12
Delta
SkyTeam
DL 5523
Delta
Canadair Regional Jet 900
Y
W
J
F
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