Southwest Airlines
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United States
McGhee Tyson Airport
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United States
Tampa International Airport
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Scan through all non-stop flights from Knoxville to Tampa. The full flight schedule below gives an overview of all non-stop flights from TYS to TPA, which includes the daily timetable of every operating airline for the upcoming 12 months.
Note: for airline-specific flight schedules, please scroll further down.
Tampa is a humid subtropical or warm-temperate destination, featuring hot, humid summers with temperatures typically around 30°C (86°F) and mild to cool winters. The region is known for consistent rainfall throughout the year, peaking in summer. The area is known for its vibrant urban energy, diverse landscapes, and numerous outdoor activities.
You can visit Tampa any time of the year, but the best months to explore are from to and from to .

Currently, there is only one airline operating non-stop flights from Knoxville TYS to Tampa TPA, which is Southwest Airlines. This section gives an overview of the flight schedules and timetables of every airline with direct flights for this route.
Click an airline below to view their TYS TPA flight schedule.
Flights from TYS to TPA are operated once a week. All flights depart at 13:35.
On this non-stop route, you can fly in Economy only.
The fastest direct flight from Knoxville to Tampa takes 1 hour and 45 minutes. The flight distance between Knoxville and Tampa is 547 miles (or 880 km).
There are 2 airports in Tampa: Tampa International Airport (TPA) and St. Petersburg-Clearwater International Airport (PIE).
There is 1 flight per week flying from Knoxville to Tampa (as of April 2026).
1 hour and 45 minutes is the average flight time from Knoxville to Tampa.
The distance from Knoxville to Tampa is 547 miles (880 kilometers).
Southwest Airlines is the only airline flying nonstop from Knoxville to Tampa.
There are no alliances flying direct from Knoxville to Tampa at the moment.
You can fly non-stop in Economy only.
Aircraft types that fly from Knoxville to Tampa:
The earliest flight departs at 13:35 from Knoxville and arrives at 15:20 at Tampa.
The latest flight departs at 13:35 from Knoxville and arrives at 15:20 at Tampa.
547 miles (880 km) · 1h 45m
13:35
15:20
Southwest Airlines
WN 1585
Southwest Airlines
Boeing 737 MAX 8
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